NEGATIVE PRESSURE RESPIRATION, WATER DIURESIS AND NATRIURESIS IN NORMOTENSIVE, HYPERTENSIVE AND PREHYDRATED NORMOTENSIVE SUBJECTS *

Negative pressure respiration, water diuresis and natriuresis in normotensive, hypertensive and prehydrated normotensive subjects.

Sieker, Gauer and Henry (1), examining nor-motensive subjects, have demonstrated that breathing against continuous negative pressure elicits a moderate water diuresis, believed to be mediated by stretch receptors in the left atrium and reflex inhibition of the secretion of the antidiuretic hormone. This water diuresis, which has been confirmed by others (2-4) is not accompanied in nor-motensive...

Pulse pressure and cardiovascular mortality in normotensive and hypertensive subjects.

There is now increasing evidence that high pulse pressure, which is an indicator of large artery stiffness, is an independent risk factor for cardiovascular mortality, especially coronary mortality, in different populations. We have recently shown in a large French population that in male subjects aged 40 to 69 years, increased pulse pressure was a strong predictor of cardiovascular mortality, ...

Climatic effects on blood pressure in normotensive and hypertensive subjects.

In a retrospective within-patient study, the arterial pressures of 174 normotensive and 50 hypertensive subjects in winter and summer were compared. Both systolic and diastolic pressures were higher in winter in the two groups but the differences were small and reached statistical significance only in the case of systolic pressure in normotensive subjects.

Autonomic Function in Hypertensive and Normotensive Subjects

Normotensive and Hypertensive Rats

We evaluated whether vascular kallikrein is altered in rats with genetic or experimental hypertension. Group 1 was infused intraperitoneally with angiotensin II (Ang II) or vehicle for 4 weeks; group 2 was injected subcutaneously with deoxycorticosterone (75 ^unol/kg once a week) or vehicle for 4 weeks; group 3 consisted of uninephrectomized rats on high sodium intake given deoxycorticosterone ...